产品货号：
GS4717
中文名称：
重组大鼠CDNF
英文名称：
Recombinant Rat Cerebral Dopamine Neurotrophic Factor
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 18.8kDa,a single non-glycosylated polypeptide chain containing 163 amino acids.
储存条件：冷冻（-20℃）
概述
Cerebral dopamine neurotrophic factor(CDNF),also known as ARMET-like protein 1,is encoded by the CDNF gene and widely expressed in neuronal and non-neuronal tissues.The CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor(GDNF).Furthermore,it also prevents the 6-hydroxydopamine(6-OHDA)-induced degeneration of dopaminergic neurons.By research,CDNF might be beneficial for the treatment of Parkinsons disease.Recombinant rat CDNF contains 163 amino acid residues and it shares 84%and 87%a.a.sequence identity with human and murine CDNF.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组大鼠CDNF，CDNF, Rat
储存条件：冷冻（-20℃）
概述
Cerebral dopamine neurotrophic factor(CDNF),also known as ARMET-like protein 1,is encoded by the CDNF gene and widely expressed in neuronal and non-neuronal tissues.The CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor(GDNF).Furthermore,it also prevents the 6-hydroxydopamine(6-OHDA)-induced degeneration of dopaminergic neurons.By research,CDNF might be beneficial for the treatment of Parkinsons disease.Recombinant rat CDNF contains 163 amino acid residues and it shares 84%and 87%a.a.sequence identity with human and murine CDNF.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.It is able to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons when immobilized at 5 - 25μg/mL on a nitrocellulose-coated microplate. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 0.1 EU/μg of rRtCDNF as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | QGLEAGVRSR ADCEVCKEFL NRFYNSLLTR GIDFSVDTIE EELISFCADT KGKENRLCYY LGATKDSATK ILGEVTRPMS VHMPTVKICE KLKKMDSQIC ELKYEKKLDL ESVDLWKMRV AELKQILHSW GEECRACAEK HDYVNLIKEL APKYVETRPQ TEL |
相关搜索：重组大鼠CDNF，CDNF, Rat